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Ruth Leben, Ph.D. in Biomedical Sciences

Ruth Leben
Bildquelle: privat

Institut für Immunologie - AG Hartmann

und Deutsches Rheuma-Forschungszentrum (DRFZ) - AG Niesner

Wissenschaftliche Mitarbeiterin (Drittmittel)

Robert-von-Ostertag-Str. 7
Raum 240
14163 Berlin

Since 2022

  • Movement of nematodes in the mouse gut using two-photon microscopy and fluorescence lifetime imaging (FLIM) as a method for imaging host and parasite metabolism and monitoring the mucus viscosity.

Until 2021

  • Intravital multi-photon microscopy, in particular FLIM of the metabolic enzyme NAD(P)H and the FRET construct TN-XXL.
  • Development of an algorithm based on the phasor approach to analyze and map metabolic enzyme activity using NAD(P)H-FLIM.
  • Calculation and mapping of the absolute intercellular calcium concentration using vector analysis of the TN-XXL donor fluorescence lifetime.
  • Two-photon excitation spectra of various fluorescent proteins.


ORCID: 0000-0001-8188-2890