Project P07 centrally supports the project groups of the 3RTG. It investigates stress biomarkers in host–pathogen infection models, focusing on glucocorticoid metabolism and its behavioural relevance. The project also explores novel biomarkers and epigenetic changes for improved disease tracking and model refinement.

Key points:

• Characterisation of glucocorticoid profiles via the HPA axis (metabolised in a species-specific but not yet fully explored manner)
• Identification of novel biomarkers and epigenetic changes
• Application in disease diagnosis, monitoring, and model refinement