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Dr. Sebastian Rausch

Project B5: Differential instruction of Th2 cells during nematode and tick infections

PhD students: Nicole Affinass (B5-1), Bhavya Kapse (B5-2), Ivet Yordanova (associated 1)

Sebastian Rausch
Image Credit: Institut für Immunologie

Freie Universität Berlin

Department of Veterinary Medicine

Institute of Immunology

Research interest:

  • Infection Biology
  • Immunology

Midha, A.; Ebner, F.; Schlosser-Brandenburg, J.; Rausch, S.; Hartmann, S. (2020)
Trilateral relationship: Ascaris, microbiota, and host cells.
Trends in parasitology, S. 2049
doi: 10.1016/j.pt.2020.09.002

Yordanova, I. A.; Lamatsch, M.; Kühl, A. A.; Hartmann, S.; Rausch, S. (2020)
Eosinophils are dispensable for the regulation of IgA and Th17 responses in Giardia muris infection.
Parasite Immunol, S. e12791
doi: 10.1111/pim.12791

Yordanova I.A.; Cortés A.; Klotz C., Kühl A.A.; Heimesaat M.M.; Cantacessi C.; Hartmann S.; Rausch S. (2019)
RORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection.
Sci Rep 9(1), 20328
doi: 10.1038/s41598-019-56416-9

Yordanova I*, Zakovic S*, Rausch S, CostaG, Levashina E, Hartmann S (2018)
Micromanaging immunity in the murine hosts versus mosquito vectors: microbiota-dependent immune responses to intestinal parasites.
Front Cell Infect Microbiology, 8:308.
doi: 10.3389/fcimb.2018.00308

Rausch S, Midha A, Kuhring M, Affinass N, Radonic A, Kühl AA, Bleich A, Renard BY, Hartmann S. (2018)
Parasitic nematodes exert antimicrobial activity and benefit from microbiota-driven support for host immune regulation. Frontiers in Immunology
ISSN: 1521-4141, DOI: 10.1002/eji.201847639 Pubmed: 30267404

Affinass N, Löhning M, Hartmann S, Rausch S
Manipulation of the balance between Th2 and Th2/1 hybrid cells effects parasite nematode fitness.
Eur J Immunol
doi: 10.1002/eji.201847639

Ahmed, N; French T, Rausch S, Kühl A, Hemminger K, Dunay I, Steinfelder S, Hartmann, S. (2017):
Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response.; Frontiers in cellular and infection microbiology; Volume 7(Article 341), S. 1–12
doi: 10.3389/fcimb.2017.00341; ISSN: 2235-2988

Bock, C.; Babu, S.; Breloer, M.; Rajamanickam, A.; Boothra, Y.; Brunn, M.-L.; Kühl, A. A.; Merle, R.; Löhning, M.; Hartmann, S.; Rausch, S. (2017):
Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells.; Front Cell Infect Microbiol; Vol. 7(Article 261), S. 1–15;
doi: 10.3389/fcimb.2017.00261

Maaz, D.; Rausch, S; Richter, D; Krücken, J; Kühl, AA; Demeler, J; Blümke, J; Matuschka, F.-R.; Samson-Himmelstjerna, G. v.; Hartmann, S (2016):
Susceptibility to ticks and Lyme disease spirochetes is not affected in mice co-infected with nematodes.; Infection and immunity; 84(5), S. 1274–1286
doi: 10.1128/IAI.01309-15, Pubmed: 26883594

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