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PD Dr. Jürgen Krücken

Project A5: Metabolism of macrocyclic lactones and benzimidazoles in parasitic nematodes
PhD student: Esra Yilmaz (A5-1), Natalie Jakobs (A5-2)

Freie Universität Berlin

Department of Veterinary Medicine

Institute of Parasitology and Tropical Veterinary Medicine

Research interest:

  • Molecular Parasitology

Gerhard, A.P.; Krücken, J.; Heitlinger, E.; Janssen, I.J.; Basiaga, M., Kornaś, S.; Beier, C.; Nielsen, M.K.; Davis, R.E.; Wang, J.; von Samson-Himmelstjerna, G. (2020)
The P-glycoprotein repertoire of the equine parasitic nematode Parascaris univalens
Sci. Rep.; Volume 10, Article no.: 13586
doi: 10.1038/s41598-020-70529-6

Bredtmann CM, Krücken J, Kuzmina T, Louro M, Madeira de Carvalho LM, von Samson-Himmelstjerna G. (2019)
Nuclear and mitochondrial marker sequences reveal close relationship between Coronocyclus coronatus and a potential Cylicostephanus calicatus cryptic species complex.
Infect Genet Evol. 2019 Jul 9:103956.
doi: 10.1016/j.meegid.2019.103956. [Epub ahead of print]

Bredtmann CM, Krücken J, Murugaiyan J, Balard A, Hofer H, Kuzmina TA, von Samson-Himmelstjerna G. (2019)
Concurrent Proteomic Fingerprinting and Molecular Analysis Of Cyathostomins.
Proteomics. 2019 Feb 20:e1800290.
doi: 10.1002/pmic.201800290

Yilmaz, E, Wongkamchai, S, Ramünke, S, Koutsovoulos, Blaxter, M, Popper, S, Schaper, R, von Samson-Himmelstjerna G, Krücken,J. (2018):
High genetic diversity in the Dirofilaria repens species complex revealed by complete and partial mitochondrial genomes of canine and feline microfilaria samples from Thailand.
Transboundary and Emerging Diseases
doi: 10.1111/tbed.13033

Bredtmann C, Krücken J, Murugaiyan J, Kuzmina T, von Samson-Himmelstjerna G (2017)
Nematode Species Identification—Current Status, Challenges and Future Perspectives for Cyathostomins, Front Cell Infect Microbiol.; 7: 283.
doi: 10.3389/fcimb.2017.00283, PMCID: PMC5487379

Yilmaz E, Ramünke S, Demeler J, Krücken J. (2017):
Comparison of constitutive and thiabendazole-induced expression of five cytochrome P450 genes in fourth-stage larvae of Haemonchus contortus isolates with different drug susceptibility identifies one gene with high constitutive expression in a multi-resistant isolate.; Int J Parasitol Drugs Drug Resist
doi: 10.1016/j.ijpddr.2017.10.001, PMID: 29035734 , PMCID: PMC5645160

Maaz, D.; Rausch, S; Richter, D; Krücken, J; Kühl, AA; Demeler, J; Blümke, J; Matuschka, F.-R.; Samson-Himmelstjerna, G. v.; Hartmann, S (2016):
Susceptibility to ticks and Lyme disease spirochetes is not affected in mice co-infected with nematodes.; Infection and immunity; 84(5), S. 1274–1286
doi: 10.1128/IAI.01309-15, Pubmed: 26883594

Yilmaz E, Fritzenwanker M, Pantchev N, Lendner M, Wongkamchai S, Otranto D, Kroidl I, Dennebaum M, Thanh H, Tran A, Ramünke S, Schaper R, von Samson-Himmelstjerna G, Krücken, J (2016):
The mitochondrial genomes of the zoonotic canine filarial parasites Dirofilaria (Nochtiella) repens and Candidatus Dirofilaria (Nochtiella) hongkongensis provide evidence for presence of cryptic species. PLoS Negl Trop Dis 10:e0005028. doi:10.1371/journal.pntd.0005028. (GRK not acknowledged).

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