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Dr. Oren Moscovitz

Participating researcher in project A3: P. falciparum glycans in adaptive immune recognition and their vaccine potential: PhD students: Felix Goerdeler (A3-2) and Jost Lühle (A3-3).

Oren Moscovitz

Max Planck Institute of Colloids and Interfaces

Biomolekulare Systeme Glycan-Targeted Therapeutics

Research interest:

  • Glycan-Targeted Therapeutics

Goerdeler F, Reuber EE, Lühle J, Leichnitz S, Freitag A, Nedielkov R, Groza R, Ewers H, Möller HM, Seeberger PH, Moscovitz O. (2023).
Thiol-Mediated Uptake of a Cysteine-Containing Nanobody for Anticancer Drug Delivery.
ACS Cent Sci 9:1111-8. doi: 10.1021/acscentsci.3c00177.

Khilji SK, Op 't Hoog C, Warschkau D, Lühle J, Goerdeler F, Freitag A, Seeberger PH, Moscovitz O. (2023).
Smaller size packs a stronger punch - Recent advances in small antibody fragments targeting tumour-associated carbohydrate antigens.
Theranostics 13:3041-3063. doi: 10.7150/thno.80901.

Khilji SK*, Goerdeler F*, Frensemeier K, Warschkau D, Lühle J, Fandi Z, Schirmeister F, Chen ZA, Turak O, Mallagaray A, Boerno S, Timmermann B, Rappsilber J, Seeberger PH, Moscovitz O. (2022).
Generation of glycan-specific nanobodies.
Cell Chem Biol Jun 6:S2451-9456(22)00199-4. doi: 10.1016/j.chembiol.2022.05.007.*equal contribution

Ben Ami Pilo H*, Khilji SK*, Lühle J*, Biskup K, Gal BL, Rosenhek Goldian I, Alfandari D, Revach OY, Kiper E, Morandi MI, Rotlopf R, Porat Z, Blanchard V, Seeberger PH, Regev-Rudzki N, Moscovitz O. (2022).
Sialylated N-glycans mediate monocyte uptake of extracellular vesicles secreted from Plasmodium falciparum-infected red blood cells.
J Extracellular Biol 1:e33. doi: 10.1002/jex2.33. *equal contribution

Midha A, Goyette-Desjardins G, Goerdeler F, Moscovitz O, Seeberger PH, Tedin K, Bertzbach LD, Lepenies B, Hartmann S. (2021).
Lectin-Mediated Bacterial Modulation by the Intestinal Nematode Ascaris suum.
Int J Mol Sci 22:8739. doi: 10.3390/ijms22168739.

Goerdeler F, Seeberger PH, Moscovitz O. (2021).
Unveiling the Sugary Secrets of Plasmodium Parasites.
Front Microbiol 12:712538. doi: 10.3389/fmicb.2021.712538.

Varela-Aramburu S, Ghosh C, Goerdeler F, Priegue P, Moscovitz O, Seeberger PH. (2020).
Targeting and Inhibiting Plasmodium falciparum Using Ultra-small Gold Nanoparticles.
ACS Appl Mater Interfaces 12:43380–7. doi: 10.1021/acsami.0c09075.

Budde S, Goerdeler F, Floß J, Kreitmeier P, Hicks EF, Moscovitz O, Seeberger PH, Davies HML, Reiser O. (2020).
Visible-light mediated oxidative ring expansion of anellated cyclopropanes to fused endoperoxides with antimalarial activity.
Org Chem Front doi: 10.3389/fcimb.2019.00046. (GRK 2046 not acknowledged)

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