Member since: July 2021

Students' representative: November 2021 - October 2022

Research interest

Title of PhD project

Manipulation of embryonated A. suum eggs with non-linear ultra-short laser impulses

Supervisors
Univ.-Prof. Dr. Susanne Hartmann/ Jun.-Prof. Dr. Friederike Ebner

Musimbi ZD, Kundik A, Krücken J, Hauser AE, Rausch S, Seeberger PH, Niesner R, Leben R, Hartmann S. (2025). 
Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure.
Sci Rep 15:2056. doi: 10.1038/s41598-025-85780-yt.

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Midha A, Oser L, Schlosser-Brandenburg J, Laubschat A, Mugo RM, Musimbi ZD, Höfler P, Kundik A, Hayani R, Adjah J, Groenhagen S, Tieke M, Elizalde-Velázquez LE, Kühl AA, Klopfleisch R, Tedin K, Rausch S, Hartmann S. (2024).
Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs.
mSphere Aug 14:e0047824. doi: 10.1128/msphere.00478-24.

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Elizalde-Velázquez LE, Schlosser-Brandenburg J, Laubschat A, Oser L, Kundik A, Adjah J, Groenhagen S, Kühl AA, Rausch S, Hartmann S. (2024).
Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection.
Sci Rep 14:14919. doi: 10.1038/s41598-024-65281-0.

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Mugo RM, Oser L, Midha A, Adjah J, Kundik A, Laubschat A, Höfler P, Musimbi ZD, Hayani R, Schlosser-Brandenburg J, Hartmann S, Rausch S. (2024).
Acute Ascaris infection impairs effector functions of natural killer cells in single and Salmonella co-infected pigs.
Sci Rep 14:14586. doi: 10.1038/s41598-024-64497-4.

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Oser L, Midha A, Schlosser-Brandenburg J, Rausch S, Mugo RM, Kundik A, Elizalde-Velázquez LE, Adjah J, Musimbi ZD, Klopfleisch R, Helm CS, von Samson-Himmelstjerna G, Hartmann S, Ebner F. (2024).
Ascaris suum infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion.
Front Immunol 15:1396446. doi: 10.3389/fimmu.2024.1396446.

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Kundik A, Musimbi ZD, Krücken J, Hildebrandt T, Kornilov O, Hartmann S, Ebner F. (2023).
Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction.
Parasit Vectors 16:243. doi: 10.1186/s13071-023-05871-5.

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Hamid B, Ebner F, Bechtold L, Kundik A, Rausch S, Hartmann S. (2022).
Ascaris suum excretory/secretory products differentially modulate porcine dendritic cell subsets.
Front Immunol 13:1012717. doi: 10.3389/fimmu.2022.1012717.