Member since: July 2021

Research interest

Title of PhD project
Effect of malaria-helmínth coinfection an immune and gut responses

Supervisors
Univ.-Prof. Dr. Susanne Hartmann/ Dr. Sebastian Rausch

Adjah J, D Musimbi Z, Mugo RM, Midha A, Hartmann S, Rausch S. (2025).
Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses.
Front Immunol 16:1483274. doi: 10.3389/fimmu.2025.1483274.

Musimbi ZD, Kundik A, Krücken J, Hauser AE, Rausch S, Seeberger PH, Niesner R, Leben R, Hartmann S. (2025). 
Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure.
Sci Rep 15:2056. doi: 10.1038/s41598-025-85780-yt.

Midha A, Oser L, Schlosser-Brandenburg J, Laubschat A, Mugo RM, Musimbi ZD, Höfler P, Kundik A, Hayani R, Adjah J, Groenhagen S, Tieke M, Elizalde-Velázquez LE, Kühl AA, Klopfleisch R, Tedin K, Rausch S, Hartmann S. (2024).
Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs.
mSphere Aug 14:e0047824. doi: 10.1128/msphere.00478-24.

Mugo RM, Oser L, Midha A, Adjah J, Kundik A, Laubschat A, Höfler P, Musimbi ZD, Hayani R, Schlosser-Brandenburg J, Hartmann S, Rausch S. (2024).
Acute Ascaris infection impairs effector functions of natural killer cells in single and Salmonella co-infected pigs.
Sci Rep 14:14586. doi: 10.1038/s41598-024-64497-4.

Mugo RM, Rausch S, Musimbi ZD, Strube C, Raulf MK, Landt O, Gichuki PM, Ebner F, Mwacharo J, Odiere MR, Ndungu FM, Njomo DW, Hartmann S. (2024).
Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for mon-itoring of human ascariasis in endemic settings.
PLOS Negl Trop Dis 18:e0012279. doi: 10.1371/journal.pntd.0012279.

Oser L, Midha A, Schlosser-Brandenburg J, Rausch S, Mugo RM, Kundik A, Elizalde-Velázquez LE, Adjah J, Musimbi ZD, Klopfleisch R, Helm CS, von Samson-Himmelstjerna G, Hartmann S, Ebner F. (2024).
Ascaris suum infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion.
Front Immunol 15:1396446. doi: 10.3389/fimmu.2024.1396446.

Kundik A, Musimbi ZD, Krücken J, Hildebrandt T, Kornilov O, Hartmann S, Ebner F. (2023).
Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction.
Parasit Vectors 16:243. doi: 10.1186/s13071-023-05871-5.