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DFG GRK1673 List of Publications

Publications by doctoral students, research students and postdocs of GRK1673 in Berlin and Hyderabad


Adel, S., K. Hofheinz, D. Heydeck, H. Kühn, and A. K. Hafner. "Phosphorylation Mimicking Mutations of Alox5 Orthologs of Different Vertebrates Do Not Alter Reaction Specificities of the Enzymes." Biochim Biophys Acta 1841, no. 10 (2014): 1460-1466.


Alvi, A., S. A. Ansari, N. Z. Ehtesham, M. Rizwan, S. Devi, L. A. Sechi, I. A. Qureshi, S. E. Hasnain, and N. Ahmed. "Concurrent Proinflammatory and Apoptotic Activity of a Helicobacter pylori Protein (Hp986) Points to Its Role in Chronic Persistence." PLoS One 6, no. 7 (2011): e22530.


Ansari, S. A., S. Devi, S. Tenguria, A. Kumar, and N. Ahmed. "Helicobacter pylori Protein Hp0986 (Tiea) Interacts with Mouse Tnfr1 and Triggers Proinflammatory and Proapoptotic Signaling Pathways in Cultured Macrophage Cells (Raw 264.7)." Cytokine 68, no. 2 (2014): 110-7.


Apoorv, T. S., P. P. Babu, S. Meese, P. P. Gai, G. Bedu-Addo, and F. P. Mockenhaupt. "Matrix Metalloproteinase-9 Polymorphism 1562 C > T (Rs3918242) Associated with Protection against Placental Malaria." American Journal of Tropical Medicine and Hygiene 93, no. 1 (2015): 186-188.


Avasthi, T. S., S. H. Devi, T. D. Taylor, N. Kumar, R. Baddam, S. Kondo, Y. Suzuki, H. Lamouliatte, F. Megraud, and N. Ahmed. "Genomes of Two Chronological Isolates (Helicobacter Pylori 2017 and 2018) of the West African Helicobacter pylori Strain 908 Obtained from a Single Patient." J Bacteriol 193, no. 13 (2011): 3385-6.


Avasthi, T. S., N. Kumar, R. Baddam, A. Hussain, N. Nandanwar, S. Jadhav, and N. Ahmed. "Genome of Multidrug-Resistant Uropathogenic Escherichia coli Strain Na114 from India." J Bacteriol 193, no. 16 (2011): 4272-3.


Banthiya, S., M. Pekárová, H. Kuhn, and D. Heydeck. "Secreted Lipoxygenase from Pseudomonas Aeruginosa Exhibits Biomembrane Oxygenase Activity and Induces Hemolysis in Human Red Blood Cells." Arch Biochem Biophys 584, (2015): 116-124.

Bauer, B., E. Pang, C. Holland, M. Kessler, S. Bartfeld, and T. F. Meyer. "The Helicobacter pylori Virulence Effector Caga Abrogates Human Beta-Defensin 3 Expression Via Inactivation of Egfr Signaling." Cell Host Microbe 11, no. 6 (2012): 576-86.


Bedu-Addo, G., P. P. Gai, S. Meese, T. A. Eggelte, K. Thangaraj, and F. P. Mockenhaupt. "Reduced Prevalence of Placental Malaria in Primiparae with Blood Group O." Malar J 13, no. 1 (2014): 289.


Bedu-Addo, G., S. Meese, and F. P. Mockenhaupt. "An Atp2b4 Polymorphism Protects against Malaria in Pregnancy." J Infect Dis 207, no. 10 (2013): 1600-3.


Böttger, E., E. Grangeiro de Carvalho, S. Meese, J. F. Kun, and M. Esen. "Expression of Interleukin-6 Family Receptors in Nk92 Cells Is Regulated by Cytokines and Not through Direct Interaction with Plasmodium falciparum-Infected Erythrocytes." J Interferon Cytokine Res 33, no. 2 (2013): 65-71.


Chaitidis, P., S. Adel, M. Anton, D. Heydeck, H. Kuhn, and T. Horn. "Lipoxygenase Pathways in Homo neanderthalensis: Functional Comparison with Homo sapiens Isoforms." J Lipid Res 54, no. 5 (2013): 1397-409.


Danilowicz-Luebert, E., N. L. O'Regan, S. Steinfelder, and S. Hartmann. "Modulation of Specific and Allergy-Related Immune Responses by Helminths." J Biomed Biotechnol 2011, (2011): 821578.


Devi, S., S. A. Ansari, J. Vadivelu, F. Megraud, S. Tenguria, and N. Ahmed. "Helicobacter Pylori Antigen Hp0986 (Tiea) Interacts with Cultured Gastric Epithelial Cells and Induces Il8 Secretion Via Nf-Kappab Mediated Pathway." Helicobacter 19, no. 1 (2014): 26-36.


Devi, S. H., T. D. Taylor, T. S. Avasthi, S. Kondo, Y. Suzuki, F. Megraud, and N. Ahmed. "Genome of Helicobacter pylori Strain 908." J Bacteriol 192, no. 24 (2010): 6488-9.


Di Venere, A., T. Horn, S. Stehling, G. Mei, L. Masgrau, A. Gonzalez-Lafont, H. Kuhn, and I. Ivanov. "Role of Arg403 for Thermostability and Catalytic Activity of Rabbit 12/15-Lipoxygenase." Biochim Biophys Acta 1831, no. 6 (2013): 1079-88.


Dittrich, N., L. C. Berrocal-Almanza, S. Thada, S. Goyal, H. Slevogt, G. Sumanlatha, A. Hussain, S. Sur, S. Burkert, D.-Y. Oh, V. Valluri, R. R. Schumann, and M. L. Conrad. "Toll-Like Receptor 1 Variations Influence Susceptibility and Immune Response to Mycobacterium Tuberculosis." Tuberculosis 95, no. 3 (2015): 328-335.


Eckert, J. K., Y. J. Kim, J. I. Kim, K. Gurtler, D. Y. Oh, S. Sur, L. Lundvall, L. Hamann, A. van der Ploeg, P. Pickkers, E. Giamarellos-Bourboulis, A. V. Kubarenko, A. N. Weber, M. Kabesch, O. Kumpf, H. J. An, J. O. Lee, and R. R. Schumann. "The Crystal Structure of Lipopolysaccharide Binding Protein Reveals the Location of a Frequent Mutation That Impairs Innate Immunity." Immunity 39, no. 4 (2013): 647-60.


Eichhorn, I., K. Heidemanns, T. Semmler, B. Kinnemann, A. Mellmann, D. Harmsen, M. F. Anjum, H. Schmidt, A. Fruth, P. Valentin-Weigand, J. Heesemann, S. Suerbaum, H. Karch, and L. H. Wieler. "Highly Virulent Non-O157 Ehec Serotypes Reflect a Similar Phylogenetic Lineage, Giving New Insights into the Evolution of Ehec." Applied and Environmental Microbiology 81, no. 20 (2015): 7041-7.


Ewers, C., F. Dematheis, S. H. Devi, N. Nandanwar, A. Fruth, I. Diehl, T. Semmler, and L. H. Wieler. "Correlation between the Genomic O454-Nlpd Region Polymorphisms, Virulence Gene Equipment and Phylogenetic Group of Extraintestinal Escherichia coli (Expec) Enables Pathotyping Irrespective of Host, Disease and Source of Isolation." Gut Pathogens 6, (2014): 37.


Fatykhova, D., A. Rabes, C. Machnik, K. Guruprasad, F. Pache, J. Berg, M. Toennies, T. T. Bauer, P. Schneider, M. Schimek, S. Eggeling, T. J. Mitchell, A. M. Mitchell, R. Hilker, T. Hain, N. Suttorp, S. Hippenstiel, A. C. Hocke, and B. Opitz. "Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue." PLoS One 10, no. 8 (2015): e0137108.


Gai, P. P., S. Meese, G. Bedu-Addo, J. B. Gahutu, and F. P. Mockenhaupt. "No Association of the P53 Codon 72 Polymorphism with Malaria in Ghanaian Primiparae and Rwandan Children." Am J Trop Med Hyg 90, no. 6 (2014): 1133-4.


Griss, K., W. Bertrams, A. Sittka-Stark, K. Seidel, C. Stielow, S. Hippenstiel, N. Suttorp, M. Eberhardt, J. Wilhelm, J. Vera, and B. Schmeck. "Micrornas Constitute a Negative Feedback Loop in Streptococcus Pneumoniae Induced Macrophage Activation." J Infect Dis, (2016). Ahead of print


Grozdanovic, Z., L. C. Berrocal-Almanza, Surabhi Goyal, A. Hussain, T. E. Klassert, D. Driesch, V. Tokaryeva, Y. Löschmann, G. Sumanlatha, N. Ahmed, V. Valluri, R. R. Schumann, B. Lala, and H. Slevogt. "A Novel Reading Scheme for Assessing the Extent of Radiographic Abnormalities and Its Association with Disease Severity in Sputum Smear-Positive Tuberculosis: An Observational Study in Hyderabad/India." PLoS One 10, no. 9 (2015).


Guenther, S., J. Wuttke, A. Bethe, J. Vojtěch, K. Schaufler, T. Semmler, R. G. Ulrich, L. H. Wieler, and C. Ewers. "Is Fecal Carriage of Extended-Spectrum-Β-Lactamase-Producing Escherichia Coli in Urban Rats a Risk for Public Health?" Antimicrobial Agents and Chemotherapy 57, no. 5 (2013): 2424-2425.


Hamann, L., A. Koch, S. Sur, N. Hoefer, C. Glaeser, S. Schulz, M. Gross, A. Franke, U. Nothlings, K. Zacharowski, and R. R. Schumann. "Association of a Common Tlr-6 Polymorphism with Coronary Artery Disease - Implications for Healthy Ageing?" Immun Ageing 10, no. 1 (2013): 43.


Hofheinz, K., K. R. Kakularam, S. Adel, M. Anton, A. Polymarasetty, P. Reddanna, H. Kühn, and T. Horn. "Conversion of Pro-Inflammatory Murine Alox5 into an Anti-Inflammatory 15s-Lipoxygenating Enzyme by Multiple Mutations of Sequence Determinants." Arch Biochem Biophys 530, no. 1 (2013): 40-7.


Horn, T., I. Ivanov, A. Di Venere, K. R. Kakularam, P. Reddanna, M. L. Conrad, C. Richter, P. Scheerer, and H. Kühn. "Molecular Basis for the Catalytic Inactivity of a Naturally Occurring near-Null Variant of Human Alox15." Biochim Biophys Acta 1831, no. 12 (2013): 1702-13.


Horn, T., K. Reddy Kakularam, M. Anton, C. Richter, P. Reddanna, and H. Kühn. "Functional Characterization of Genetic Enzyme Variations in Human Lipoxygenases." Redox Biol 1, no. 1 (2013): 566-77.


Hussain, A., C. Ewers, N. Nandanwar, S. Guenther, S. Jadhav, L. H. Wieler, and N. Ahmed. "Multiresistant Uropathogenic Escherichia Coli from a Region in India Where Urinary Tract Infections Are Endemic: Genotypic and Phenotypic Characteristics of Sequence Type 131 Isolates of the Ctx-M-15 Extended-Spectrum-Beta-Lactamase-Producing Lineage." Antimicrob Agents Chemother 56, no. 12 (2012): 6358-65.


Hussain, A., A. Ranjan, N. Nandanwar, A. Babbar, S. Jadhav, and N. Ahmed. "Genotypic and Phenotypic Profiles of Escherichia coli Isolates Belonging to Clinical St131, Clinical Non-St131 and Faecal Non-St131 Lineages from India." Antimicrobial Agents and Chemotherapy 58, no. 12 (2014): 7240-9.


Ivanov, I., A. Di Venere, T. Horn, P. Scheerer, E. Nicolai, S. Stehling, C. Richter, E. Skrzypczak-Jankun, G. Mei, M. Maccarrone, and H. Kühn. "Tight Association of N-Terminal and Catalytic Subunits of Rabbit 12/15-Lipoxygenase Is Important for Protein Stability and Catalytic Activity." Biochim Biophys Acta 1811, no. 12 (2011): 1001-10.


Jadhav, S., A. Hussain, S. Devi, A. Kumar, S. Parveen, N. Gandham, L. H. Wieler, C. Ewers, and N. Ahmed. "Virulence Characteristics and Genetic Affinities of Multiple Drug Resistant Uropathogenic Escherichia coli from a Semi Urban Locality in India." PLoS One 6, no. 3 (2011): e18063.


Khattak, F. A., A. Kumar, E. Kamal, R. Kunisch, and A. Lewin. "Illegitimate Recombination: An Efficient Method for Random Mutagenesis in Mycobacterium avium Subsp. hominissuis." BMC Microbiol 12, (2012): 204.


Kolb, J., D. Hillemann, P. Mobius, J. Reetz, A. Lahiri, A. Lewin, S. Rusch-Gerdes, and E. Richter. "Genetic Characterization of German Mycobacterium avium Strains Isolated from Different Hosts and Specimens by Multilocus Sequence Typing." Int J Med Microbiol 304, no.8 (2014): 941-8.


Krücken, J., C. Schreiber, D. Maaz, M. Kohn, J. Demeler, S. Beck, E. Schein, P. Olias, D. Richter, F. R. Matuschka, S. Pachnicke, K. Krieger, B. Kohn, and G. von Samson-Himmelstjerna. "A Novel High-Resolution Melt Pcr Assay Discriminates Anaplasma Phagocytophilum and "Candidatus Neoehrlichia Mikurensis"." J Clin Microbiol 51, no. 6 (2013): 1958-61.


Kühn, H., S. Banthiya, and K. van Leyen. "Mammalian Lipoxygenases and Their Biological Relevance." Biochimica et biophysica acta 1851, no. 4 (2015): 308-30.


Kumar, A., A. Lewin, P. S. Rani, I. A. Qureshi, S. Devi, M. Majid, E. Kamal, S. Marek, S. E. Hasnain, and N. Ahmed. "Dormancy Associated Translation Inhibitor (Datin/Rv0079) of Mycobacterium Tuberculosis Interacts with Tlr2 and Induces Proinflammatory Cytokine Expression." Cytokine 64, no. 1 (2013): 258-64.


Kumar, A., M. Majid, R. Kunisch, P. S. Rani, I. A. Qureshi, A. Lewin, S. E. Hasnain, and N. Ahmed. "Mycobacterium tuberculosis Dosr Regulon Gene Rv0079 Encodes a Putative, 'Dormancy Associated Translation Inhibitor (Datin)'." PLoS One 7, no. 6 (2012): e38709.


Lahiri, A., J. Kneisel, I. Kloster, E. Kamal, and A. Lewin. "Abundance of Mycobacterium avium Ssp. hominissuis in Soil and Dust in Germany - Implications for the Infection Route." Lett Appl Microbiol 59, no. 1 (2014): 65-70.


Lahiri, A., A. Sanchini, T. Semmler, H. Schäfer, and A. Lewin. "Identification and Comparative Analysis of a Genomic Island in Mycobacterium avium Subsp. hominissuis." FEBS Letters 588, no. 21 (2014): 3906-11.


Nandanwar, N., T. Janssen, M. Kuhl, N. Ahmed, C. Ewers, and L. H. Wieler. "Extraintestinal Pathogenic Escherichia Coli (Expec) of Human and Avian Origin Belonging to Sequence Type Complex 95 (Stc95) Portray Indistinguishable Virulence Features." Int J Med Microbiol 304, no.7 (2014): 835-42.


Nieradka, Andrzej, Christoph Ufer, Klaske Thiadens, Godrey Grech, Ratislav Horos, Marleen van Coevorden-Hameete, Emile van den Akker, Sajad Sofi, Hartmut Kühn, and Marieke von Lindern. "Grsf1-Induced Translation of the Snare Protein Use1 Is Required for Expansion of the Erythroid Compartment." PLoS One 9, no.4 (2014): e104631. 


O'Regan, N. L., S. Steinfelder, C. Schwedler, G. B. Rao, Aparna Srikantam, V. Blanchard, and S. Hartmann. "Filariasis Asymptomatically Infected Donors Have Lower Levels of Disialylated Igg Compared to Endemic Normals." Parasite Immunology 36, no. 12 (2014): 713-20.


O'Regan, N. L., S. Steinfelder, G. Venugopal, G. B. Rao, R. Lucius, Aparna Srikantam, and S. Hartmann. "Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses." PLoS Neglected Tropical Diseases 8, no. 10 (2014): e3206.


Povolotsky, T. L., and R. Hengge. "'Life-Style' Control Networks in Escherichia Coli: Signaling by the Second Messenger C-Di-Gmp." J Biotechnol 160, no. 1-2 (2012): 10-6.


Povolotsky, T. L., and R. Hengge. "Genome-Based Comparison of C-Di-Gmp Signaling in Pathogenic and Commensal Escherichia Coli Strains." Journal of Bacteriology 198, no. 1 (2015): 111-26.


Rabes, A., S. Zimmermann, K. Reppe, R. Lang, P. H. Seeberger, N. Suttorp, M. Witzenrath, B. Lepenies, and B. Opitz. "The C-Type Lectin Receptor Mincle Binds to Streptococcus Pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response." PLoS One 10, no. 2 (2015): e0117022.


Richter, A. M., T. L. Povolotsky, L. H. Wieler, and R. Hengge. "Cyclic-Di-Gmp Signalling and Biofilm-Related Properties of the Shiga Toxin-Producing 2011 German Outbreak Escherichia Coli O104:H4." EMBO Molecular Medicine 6, no. 12 (2014): 1622-37.


Schaufler, K., A. Bethe, A. Lubke-Becker, C. Ewers, B. Kohn, L. H. Wieler, and S. Guenther. "Putative Connection between Zoonotic Multiresistant Extended-Spectrum Beta-Lactamase (Esbl)-Producing Escherichia Coli in Dog Feces from a Veterinary Campus and Clinical Isolates from Dogs." Infection Ecology and Epidemiology 5, (2015): 25334.


Schaufler, K., T. Semmler, L. H. Wieler, M. Wohrmann, R. Baddam, N. Ahmed, K. Muller, A. Kola, A. Fruth, C. Ewers, and S. Guenther. "Clonal Spread and Interspecies Transmission of Clinically Relevant Esbl-Producing Escherichia Coli of St410-Another Successful Pandemic Clone?" FEMS Microbiol Ecol 92, no. 1 (2016).


Semmler, T., I. Eichhorn, A. Bethe, R. Bauerfeind, D. Pickard, R. A. Kingsley, G. Dougan, and L. H. Wieler. "Genome Sequence of Porcine Escherichia coli Strain Imt8073, an Atypical Enteropathogenic E. Coli Strain Isolated from a Piglet with Diarrhea." Genome Announc 1, no. 4 (2013).


Singer, B. B., L. Opp, A. Heinrich, F. Schreiber, R. Binding-Liermann, L. C. Berrocal-Almanza, K. A. Heyl, M. M. Muller, A. Weimann, J. Zweigner, and H. Slevogt. "Soluble Ceacam8 Interacts with Ceacam1 Inhibiting Tlr2-Triggered Immune Responses." PLoS One 9, no. 4 (2014): e94106.


Steinfelder, S., N. L. O’Regan, and S. Hartmann. "Diplomatic Assistance: Can Helminth-Modulated Macrophages Act as Treatment for Inflammatory Disease?" PlosPathogens (2016). Accepted

van der Ploeg, A. H., O. Kumpf, E. Seelow, L. C. Berrocal-Almanza, P. M. Schlag, R. R. Schumann, and L. Hamann. "The Course of Gastric Cancer Following Surgery Is Associated with Genetic Variations of the Interleukin-1 Receptor Antagonist and Interleukin-1beta." Gastric Cancer 18, no. 1 (2014): 77-83.


Wuest, S. J., T. Horn, J. Marti-Jaun, H. Kühn, and M. Hersberger. "Association of Polymorphisms in the Alox15b Gene with Coronary Artery Disease." Clin Biochem 47, no. 6 (2014): 349-55.