E. coli I

Phylogenetic studies of APEC and UPEC strains using Multi-locus-Sequence-Typing


Avian pathogenic E. coli (APEC) are the causal organism of Colisepticaemia in poultry and other wild birds. Similarities, for example, the presence of identical virulence genes, imply the possibility of APEC resembling extraintestinal pathogenic E. coli (ExPEC) of human origin like the Uropathogenic (UPEC) and Newborn meningitis E. coli (NMEC). MLST studies involving a representative number of clinical isolates of extraintestinal origin from animals and humans could provide information about the existence of APEC isolates that share a common origin with these human pathogenic strains. Preliminary data suggest the presence of clonal groups among E. coli pathogenic for poultry, that are identical to the Sequence complexes identified in NMEC, and therefore the zoonotic potential of these APEC isolates should eventually be further investigated.