The scientific focus of the Institute for Immunology are infections with parasitic helminths (figure). Of particular interest to our work are the different mechanisms leading to the persistence of parasite infections in immunocompetent hosts. The long-term goal of our group is to develop intervention strategies against nematode infections in humans and animals. In addition, we are interested in immune evasion mechanisms of parasitic nematodes, which might be of use in interfering with undesired inflammatory processes such as auto-immune reactions and allergies.
1. Modulation of the innate and adaptive immune system by nematodes
2. Therapeutic potential of nematodes
3. Interaction of nematodes with coinfections
4. Nematodes and host microbiota
5. Immunological tools